2024 Es 350 Mpg. Research the 2024 lexus es 350 at cars.com and find specs, pricing, mpg, safety data, photos, videos, reviews and local inventory. The epa's fuel economy estimates for the es250 are 25 mpg city and 34 mpg highway.

1984 to present buyer’s guide to fuel efficient cars and trucks. The 2025 lexus es is a midsize luxury sedan with a smooth ride, a comfortable interior, and a powerful v6 engine.